Do you have expertise in, and a passion for providing scientific leadership? Would you like to apply your expertise to impact the successful translation and life-cycle management of IO agents already being tested in clinical trials in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!


AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.


Welcome to the Cambridge Biomedical Campus, where we will be transitioning to in 2022, one of over 400 sites here at AstraZeneca, providing a collaborative environment where everyone feels comfortable and able to be themselves is at the core of AstraZeneca’s priorities, it’s important to us that you bring your full self to work every day. To help you maintain your best self, here’s a sneak peek into some of the things this site provides for you… this new purpose-built site will bring together the company’s research and development activity in a state-of-the-art strategic R&D center and global corporate headquarters. The building has been designed with the open architecture reflecting AstraZeneca’s collaborative approach to research. Open laboratories and transparent glass walls will enable new ways of working across disciplines, whilst a central courtyard will put science on full display.


High expectations and hunger for more means we are always disrupting – challenging the norm and taking the initiative to try new things. We set the tone for the rest of the industry, consistently publishing our findings in high impact journals, and leading with expertise and entrepreneurial spirit. Everything we do has a sense of urgency, we work at pace to push forward and create better outcomes. Our story is one of success and perseverance. A journey that we’re proud to say has brought us to where we are today as a leading Oncology business. We feel a strong sense of pride and accomplishment playing our part in making a positive difference to medical science, patients and society – promoting health and wellbeing all around the world.

What you’ll do

Providing robust scientific leadership for activities within the Early Oncology, Clinical Immuno-Oncology (IO) group at AstraZeneca. You will apply your passion and deep expertise in IO to lead activities to improve successful translation and life-cycle management of IO agents already being tested in clinical trials. As a bioscience lead on cross-functional project teams you will be responsible for developing and delivering relevant pharmacology and biomarker strategy to gain a deeper understanding of mechanism and inform various aspects of clinical development; including biomarker, clinical line-of-sight and additional combination(s) strategies.

Necessarily, you will stay up to date with the latest discoveries in tumor immunology, share your expertise within (and beyond )the bioscience group, publish peer reviewed articles on your research and develop and lead external collaborations.

You will primarily matrix manage the project bioscience team, providing expert advice and mentorship, interpreting complex data and making high level recommendations. You will apply your influencing, coaching and mentoring skills to ensure effective cross-functional working within teams. Necessarily, there will be a strong working relationship with colleagues in translational sciences and partner lines allied to delivering the pharmacology. This is a global role. Although the assignment is anchored in Cambridge, many colleagues within Early Oncology (including the Clinical IO group) are located at our Gaithersburg, MD facility in the USA and the successful candidate must have the ability to work seamlessly in this regard. Lastly, there will also be a requirement to undertake some focused laboratory based work to advance your projects / train staff, as appropriate.

Essential for the role

  • PhD (or equivalent) in a biological science with research experience post-PhD in academia or industry

  • Deep expertise in tumor microenvironmental biology, plus broad understanding and enthusiasm for tumor immunology and cancer therapies

  • General knowledge of biologics drug development

  • Track record of successful scientific leadership of cross-functional scientific project teams or an academic research group lead

  • Technical expertise in preclinical models to enable successful clinical translation and biomarker profiling.

  • Excellent scientific communication skills including both written reports (e.g. manuscripts) and oral presentations to broad and diverse audiences

  • Willingness to undertake hands-on laboratory based activities to achieve project deliverables and train, oversee, coach and mentor other colleagues working on the project

Desirable for the role

  • Experience working in the field of IO drug discovery

  • Authorship of patents, grants and/or publications in top-tier scientific journals

  • Line management experience

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

There’s no better place to make an impact – here we are uniquely placed with the funding, the ambition and the bravery to make it happen.

So, what’s next?

  • Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

  • Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

  • If you’re curious to know more then please reach out to Louise Bennett

Competitive salary and benefits

Close date: 23/01/2022

Where can I find out more?

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