Associate Principal Scientist – Formulation and Drug Delivery

Associate Principal Scientist – Formulation and Drug Delivery

Location: Macclesfield

Permanent opportunity

Competitive salary and benefits

Make a positive impact, in a team where it means more

In Operations we have a big ambition – to deliver more medicines to patients, more quickly and more affordably. Backed by investment, leadership and a clear plan to get there, we bring personal dedication and out of the box thinking.

If you have the passion and the drive to accelerate growth and make people’s lives better – this is the place for you.

Business area New Modalities and Parenteral Development

To meet patients’ needs, AstraZeneca recognises the opportunity to apply a diverse range of new modality technologies to design novel therapeutics. This is exemplified by the increased number of new modalities entering clinical development – currently 30% of the early pipeline now consists of new drug modalities.

The New Modalities and Parenteral Development group has accountability for developing the pipeline of both new modality projects and traditional synthetic molecules requiring parenteral delivery.

The Associate Principal Scientist role

An exciting opportunity has arisen for an Associate Principal Scientist: Formulation and Drug Delivery in our New Modalities and Parenteral Development (NMPD) group. This is a key role in our formulation community with specific focus on delivering our existing pipeline and building capabilities for our emerging portfolio.

The role holder will have significant experience in the formulation and development of parenteral Drug Products, ideally with knowledge of approaches for both traditional small molecule and new modalities (e.g. oligonucleotides, peptides/proteins, dendrimers, mRNA). Any gaps in knowledge of approaches for specific modality types will be addressed through a combination of training and project experience.

The individual will provide expert Formulation input to the teams delivering AstraZeneca’s portfolio of drug projects and will also have a role in identifying transformative formulation technologies for the current & future portfolio.

As an Associate Principal Scientist, you will be encouraged to work collaboratively with and support colleagues from other scientific teams in AstraZeneca (analysts, process chemists, engineers etc.) and with external partners (academics, professional organisations, technology providers etc.).

This role would suit an individual who can combine technical expertise and a scientific passion with a committed, collaborative & dependable approach to delivery .

All accountabilities have a significant impact on the development of AstraZeneca’s project portfolio and building our underpinning scientific capability. Depending on the skills and experience of the successful applicant, coaching and training will be provided to ensure optimal delivery against the role.

Desirable skills & capabilities:

  • BSc/PhD level education in a relevant subject area or the equivalent in experience

  • Experience working within a Research & Development environment in the pharmaceutical industry.

  • Significant experience in Formulation & Drug Delivery with emphasis on parenteral approaches. Ideally experience/understanding of product development requirements for new modality medicines (e.g. oligonucleotides, peptides/proteins, dendrimers, mRNA).

  • Experience of technical coaching and supervision, and leading small teams of people or scientific projects

  • Understanding of existing Regulatory guidelines with experience of applying this to authoring of regulatory submissions

In NMPD we understand the importance of managing the demands of both home and work life. To support this, many of our staff work flexibly in different ways, including working part-time, regular home-working, flexible start/finish times etc. We will consider requests for flexible working for this role and encourage applicants to talk to us at interview about the flexibility you need.

Please note applications must include your current CV and a cover letter.

Why AstraZeneca…

Working with medicines to address unmet needs fills us with pride. The potential to make people’s lives better is an incredible feeling. We get to support and positively impact local and global communities, from patients and their families to all of society.

So, what’s next…

Are you ready to bring new ideas and fresh thinking to the table? Excellent! We have one seat available and we hope it’s yours!

Applications are open from 20th October to 3rd November 2021

More Information

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