Do you have expertise in, and passion for, Immuno- Oncology? Would you like to apply your expertise to a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

About AstraZeneca

At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life.

Site description

Welcome to Cambridge, one of over 400 sites here at AstraZeneca, providing a collaborative environment where everyone feels comfortable and able to be themselves is at the core of AstraZeneca’s priorities, it’s important to us that you bring your full self to work every day. To help you maintain your best self, here’s a sneak peek into some of the things this site provides for you…

Central Cambridge – Located in walking distance from the Train station, you will have access to an onsite gym, restaurant facilities and experience working within a calm and relaxing agile environment, inspired by the University Botanical gardens. You’ll also be able to enjoy Lunch & Learn development activities, all within a forward-thinking and spacious environment while utilising the most advanced technology.

Business area

AstraZeneca’s vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. A broad pipeline of next-generation medicines is focused principally on four disease areas – breast, ovarian, lung and haematological cancers.

We are seeking a highly motivated Associate Principal Scientist in Immuno-Oncology with deep scientific and technical expertise in T cell biology and a track record of successful scientific leadership to join our team in Cambridge, UK. As an experienced Project Lead within the Immuno-oncology (IO) Bioscience team, you will play a pivotal role in identifying the next generation of innovative IO therapies, and in deepening our understanding of cancer immunology.

What you’ll do

  • Working in this scientific leadership role you will apply your technical and scientific experience to discover innovative therapeutic approaches.

  • As the bioscience lead on cross-functional project teams you will be responsible for developing and delivering the preclinical strategy to advance projects through the drug discovery pipeline.

  • Stay up to date with the latest discoveries in tumour immunology, share your expertise both within and beyond the bioscience group, publish peer reviewed articles on your research and develop, and lead, external collaborations.

  • Matrix manage the project bioscience team, providing advice and mentorship, interpreting complex data and making high level recommendations.

  • Apply your influencing, coaching and mentoring skills to ensure effective cross-functional working within teams.

  • Directly lead bioscience team members, helping to set goals and objectives and coordinating their professional development.

Essential for the role

  • PhD (or equivalent) in a biological science with at least several years of research experience post-PhD in academia or industry

  • Deep expertise in immune-oncology particularly around T cell immunology, plus broad understanding and enthusiasm for translating basic science into novel cancer therapies

  • Line management experience

  • General knowledge of biologics drug development

  • Track record of successful scientific leadership (e.g. grants, patents, publications, experience leading projects through milestone transitions in industry/biotec)

  • Technical expertise in preclinical model systems that can be applied to cancer immunology research

  • Excellent scientific communication skills including both written reports (e.g. manuscripts) and oral presentations to broad and diverse audiences

Desirable for the role:

  • Experience in the field of T cell exhaustion

  • Experience working in the field of IO drug discovery

  • Experience working with successful cross-functional scientific project teams

  • Authorship of patents, grants and/or publications in top-tier scientific journals

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you. Don’t hesitate in submitting an application today!

Competitive salary and benefits package on offer.

The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, A performance recognition scheme and a competitive, generous remuneration package.

Closing date: 1st January 2022

Where can I find out more?

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We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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