The role holder provides technical leadership as either an expert lead for a number of processes or through leadership of a regional based group that ensures effective collaboration between physicians. Will develop and build, or act as a specialist expert, within a cross-functional multi-skilled team comprised of experts across multi-disciplinary project teams to design, execute, analyse and interpret clinical studies to validate novel therapeutic targets, develop novel biomarkers of pharmacological effects.

Pathologist, Associate Director or Director – Clinical Pharmacology and Safety Sciences

Cambridge, UK or Gothenburg, SE

Competitive Salary & Benefits

Meaningful Impact. Make a more meaningful contribution Impact patients’ lives every day

Make a more meaningful impact in your career, with greater ownership and accountability to make a contribution. And in return… we’re looking for people driven by making a difference to patients and society, dedicated to doing the right thing.

Strengthen our pipeline to make a meaningful impact on patients

Be part of a dedicated Research & Development team. Fuelled by our commitment to help more patients, strengthen our pipeline and grow our area.

Are you an experienced veterinary anatomic pathologist with expertise in toxicologic or disease area pathology? This is an exciting opportunity to join a global group of highly skilled pathologists that work closely with dedicated safety teams to drive the discovery and development of innovative treatments for patients. The role is broad in scope and offers significant potential for scientific collaboration and professional development.

What you will do

As a Pathologist in Clinical Pharmacology and Safety Sciences, you’ll collaborate with discovery safety specialists, toxicologists and disease area scientists, providing expert anatomic pathology support to drug projects across all development stages.

You’ll contribute to the design and assessment of investigative safety and efficacy studies, ensuring timely delivery of impactful, decision-making pathology data. In addition, you’ll provide pivotal pathology support to AstraZeneca’s new modalities team and develop pathology expertise in novel treatment modalities, including self-amplifying RNA therapeutics, and relevant delivery systems. In partnership with our expert imaging and AI scientists, you’ll explore the use of image analysis and artificial intelligence to drive quantitative pathology.

As Project Pathologist, peer review of outsourced toxicology studies is an important part of your responsibility. For individual drug projects, you’ll ensure consistency of CRO pathology outputs across toxicology studies and appropriate integration of pathology data within study reports and regulatory submissions.

Essential Requirements

  • Degree in Veterinary Medicine
  • Postgraduate pathology qualification (FRCPath, DACVP, DECVP, DJSTP or equivalent)
  • Broad cross-species toxicologic pathology expertise with experience of histopathological evaluation and peer review of short- and long-term toxicology studies
  • Ability to integrate pathology findings with a range of additional endpoints (e.g., clinical pathology, IHC, ISH, MSI) and provide contextualized interpretation for project teams
  • Highly effective written and oral communication skills with the ability to clearly convey complex pathology data to a wide range of stakeholders

Desirable Requirements

  • PhD in pathology or a related discipline
  • Track record of scientific delivery demonstrated by peer-reviewed publications in high impact/high-quality journals; ideally complimented by a strong pathology peer network
  • Relevant experience of providing discovery and toxicologic pathology support and acting as a pathology representative on multiple drug development projects; previous experience with nucleotide-based modalities would be an advantage
  • Ability to provide a holistic view of translational safety, efficacy pathology and pathophysiology from animal to patient

If you are a veterinary anatomic pathologist seeking a new challenge, please get in touch with James Cartwright (james.cartwright@astrazeneca.com) for an informal discussion about this exciting opportunity.

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

So, what’s next?

Complete your application before the below closing date.

This role is open from 23/02/2022 and we welcome your application no later than 09/03/2022.

Where can I find out more?

Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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