Principal Scientist Route Design

Location: Macclesfield, UK

Make a positive impact, in a team where it means more

Disciplined thinkers and doers, we thrive in our often intense and ambiguous environment, seeking out new challenges and working towards new solutions. A place where anyone is supported to step up and lead, and everyone has the freedom to take ownership and drive outcomes forward!

If you have the passion and the drive to accelerate growth and make people’s lives better – then this is the place for you!

Business area

PT&D is the bridge, which turns forward-thinking science into actual medicines that help millions of people. We work across the entire value chain, crafting and delivering active ingredients, formulations and devices required to support new medicines – from supplies for use in early toxicology studies and clinical trials, to developing the technology to ensure drugs can be scaled up for commercial manufacture and ultimately continuing to ensure that these medicines can be manufactured for supply to patients.

Within PT&D, in Chemical Development we believe that nothing is impossible, and we are determined to push the boundaries of science to deliver medicines to our patients. We combine people’s deep technical knowledge and understanding with their talent and drive to design, develop and optimise synthetic routes that deliver the active pharmaceutical ingredients (API) of our medicines in a sustainable, commercially viable way.

We believe in innovation and continuous improvement, working closely with colleagues in academia and across industry, we apply the newest technologies and principles in the processes we develop.

The role

We are now looking for a Principal Scientist to join our team to lead drug substance Route Design. The Principal Scientist will be accountable for designing and evolving strategy and plans to achieve Route Design within 30 days by 2025.

You will champion route design activities to all audiences internally and externally, creating a best in Industry reputation.

Other responsibilities include:

  • Being a visible role model for scientific leadership across and beyond PT&D

  • Drives Continuous Improvement across Value Streams and within own area of responsibility

  • Sponsors and leads activities within the department

  • Recognised and in demand as a problem solver for key technical challenges

  • You will have direct impact on today’s drug project portfolio, including input into Intellectual Property strategy for projects

  • Coach and lead Chemical Development scientific ladder staff

  • Awareness of the status of key technical challenges and opportunities in the current drug project portfolio

  • Proactive in linking scientists together, promoting collaboration and building technical communities across disciplines

  • Understands the industry and AZ business context and drive S&T and drug project strategy to add value

Education, Qualifications, Skills and Experience

  • BSc/PhD level education in a relevant discipline or equivalent in experience

  • Significant number of years’ experience working within a Research & Development and Manufacturing environment, within the pharmaceutical industry

  • Strong external profile demonstrating scientific leadership in Route Design

  • Demonstration of collaborative and multi-disciplinary team working to deliver a range of science and technology and drug project objectives.

  • Skilled in effective communication across a range of skills and experience levels.

Next steps

Applications are welcome from 16th July to 1st August 2021.

Competitive salary and benefits

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