Salary: £30,273- £33,180 per annum
Location: South Kensington Campus
The Department of Life Sciences was the top ranked university department in the UK for research intensity in Biological Sciences in REF2014 (Times Higher Education), scoring 100% on our environment.
We are seeking to appoint one pro-active Research Technician to provide technical support to a world-leading and dynamic research team in the Crisanti Laboratory within the Department of Life Sciences at Imperial College London.
The Crisanti Laboratory has pioneered the genetic manipulation of the human malaria mosquito and it is now focused on projects aimed at creating gene drive systems based on the use of DNA endonucleases with the ultimate goal of malaria control by decreasing the reproductive potential of mosquito populations.
The successful candidate will help to assist with independent and original research within part of a large team of postdocs and technicians within the Crisanti group at Imperial College that form part of a larger, multi-disciplinary research consortium called Target Malaria. The project is aimed at designing, building and testing novel gene drives through the incorporation of three components: nucleases with improved activity; rational choice of new genetic targets to be affected by the gene drive; modulating and regulating gene drive expression in time and space.
Duties and responsibilities
You will interact on a daily basis with researchers of the group and provide assistance in laboratory experiments applied to the generation and molecular analysis of modified mosquitoes, including learning the microinjection of mosquito embryos, and genetic crossing experiments. You will also assist in the performance of molecular diagnostic assays, fertility experiments and caged population experiments.
Duties will also include contributing to the smooth running and regulatory compliance of the two insectary facilities used by the group, including acting as a caretaker of wild type and transgenic mosquito strains, ensuring that mosquito colonies and samples are available to researchers in the group.
You must have a Bachelor Degree or equivalent vocational qualification in a biological sciences subject, plus work experience in a relevant technical/scientific roles. Good knowledge of molecular biology is essential along with practical laboratory skills. Experience in molecular biology techniques including RNA extraction, reverse transcription, polymerase chain reaction, gel electrophoresis, DNA purification, blotting and probing is also required. Previous experience of working with mosquitoes is desirable, but not essential.
Good verbal and written communication skills, accurate record keeping skills and the ability to prioritise tasks to meet deadlines tight deadlines with little supervision are essential. You must be computer literate and a highly motivated, individual with demonstrable ability to learn. You will be expected to work in a collaborative manner, be open-minded with a positive approach to develop and apply new concepts, as well as to problem solving. The project may require occasional travel to other collaborating sites within Europe and flexible working hours.
This is a full-time, fixed-term position until 31/05/2024, with the possibility of extension subject to the availability of funding.
Closing date: 17/11/2021
To apply, visit www.imperial.ac.uk/jobs and search by the job reference NAT01023.