Senior Formulation Scientist (Product Development)

Senior Formulation Scientist (Product Development)

Macclesfield, UK

Salary & Benefits Competitive

Make a more meaningful impact to patients’ lives around the globe

With our ground-breaking pipeline, the outlook is bright. Be proud to be part of a place that has achieved so much, yet is still moving forward. There’s no better time to join our global, growing enterprise as we lead the way for healthcare and society.

Pharmaceutical Technology and Development (PT&D)

PT&D utilises great science delivered by great people to develop medicines that help millions of patients worldwide. We have an opportunity for a Senior Formulation Scientist to join the New Modalities and Parenteral Development (NMPD) organisation within PT&D. Together, we create life-changing new medicines for patients through design and development of high quality products and our drive for technical excellence.

The role

As Senior Formulation Scientist you will be responsible for delivering the formulation design and product understanding to progress development of innovative medicines within a dynamic team environment.

You will work collaboratively across boundaries to achieve these goals with team members from multiple subject areas (e.g. analytical, material science, engineering, biopharmaceutics, packaging, devices, clinical, supply chain and many more).

Typical responsibilities for the successful applicant will include:

  • Rational design, development and delivery of high quality parenteral drug products including new modalities from first principles based on Target Pharmaceutical Profile requirements and patient needs.

  • Ensuring development of robust sterile products and manufacturing processes through support of their control strategies, marketing applications and downstream commercialisation activities.

  • Working effectively with colleagues across Product Development, Pharmaceutical Sciences and Operations to ensure the successful delivery of drug projects spanning all phases of development.

  • Authoring of regulatory documentation to support clinical trial and marketing applications and ensured continued and safe access of our products to patients.

  • Collaborating with others to develop Formulation Science and Technology strategies and deliver capability build.

  • Providing technical supervision and mentoring to peers and students.

  • Driving innovation, securing intellectual property and enhancing AstraZeneca’s scientific reputation by publishing high calibre research and engaging in external collaborations.

Essential Skills

  • Industrial experience in parenteral drug product development with a degree in a related scientific field or a PhD in pharmaceutics or equivalent in experience.

  • Experience in parenteral product design (including solutions and lyophiles) with an understanding of the drug development process, spanning development through to commercialisation.

  • Good understanding of how drug substance properties influence formulation and manufacturing process design and how these impact final drug product quality.

  • Strong collaborative working and communication skills, including ability to work effectively with colleagues from diverse backgrounds and skill areas.

  • Ability to work safely and follow key quality systems to ensure data integrity.

  • Good oral and written communication skills, including ability to document work clearly, concisely and describe its importance to others within the context of the wider project.

  • Good organisational and planning skills with the ability to deliver to agreed time and quality.

Desirable skills

  • Experience in development, scale up and technology transfer of sterile parenteral manufacturing processes e.g lyophilisation, sterile filtration, terminal sterilisation.

  • Experience of using predictive science techniques or digital design to support formulation development.

  • Knowledge and experience of working to Good Manufacturing Practice (GMP).

  • Experience of working with external suppliers and managing productive relationships.

  • Specialised knowledge of the theory of lyophilisation.

Please note applications must include your current CV and a covering letter.

Why AstraZeneca…

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

Next steps…

Are you ready to bring new ideas and fresh thinking to the table? Excellent! We have one seat available and we hope it’s yours!

Applications are welcome from 13th August to 5th September 2021.

More Information

Apply for this job

Privacy Policy / BBSTEM Limited | Registered in England and Wales | Company No: 11127036