This is an exciting opportunity to join the Oncology Bioscience group in Cambridge as a laboratory based senior scientist. You will become part of a large team of bioscientists and play a pivotal role in the delivery of robust and high quality in vitro data to support drug discovery projects at all stages within the Oncology portfolio. Working collaboratively with other disciplines across AstraZeneca you will have the opportunity to really drive projects forward, identifying and validating novel targets, determining the mechanism of action of new chemical series and understanding drug resistance and novel combination opportunities for clinical candidates.

You should have a background in Oncology and a strong passion for experimental work and delivering data from the laboratory. You will use your scientific judgement, ability to analyse data, lab experience and communication skills to contribute to experimental design and interpretation for either early or late stage drug discovery programmes.

About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.

Site description

Welcome to our Chesterford Research Park, one of over 400 sites here at AstraZeneca, providing a collaborative environment where everyone feels comfortable and able to be themselves is at the core of AstraZeneca’s priorities, it’s important to us that you bring your full self to work every day. To help you maintain your best self, here’s a sneak peek into some of the things this site provides for you…high quality office facilities accommodating teams from our Oncology, BioPharmaceuticals R&D Organisations. Restaurant and bar facilities within the park along with space for recreational walks and jogging paths. The park hosts a health and fitness centre and provides coach and shuttle bus services to Cambridge City centre, easily accessible via regular running public transport, you can also park at the site.

Business area

In the Oncology Business Unit we relentlessly follow the science, challenging the status quo to deliver more effective treatments to patients in need. Our dedication means we purposefully push back the limits of knowledge to change the practice of medicine. To ensure no patient is left behind, no matter what stage of disease.

Fast-paced, it takes agility and responsiveness to stay committed in our pursuit of excellence. We work with focus to seek the unanswered questions – innovating, challenging accepted norms, quick decision-making and taking smart risks. A place of trust, it’s an opportunity to take accountability, be brave, speak up, step up and redefine Oncology, now and in the future. Be a part of improving lives. This is the time to join the team who is confident that cures for cancer are within our grasp.

What you’ll do

  • Deliver high quailtiy in vitro data according to the study plan as agreed with the team leader or project supervisor

  • Provide expert interpretation of experimental data, identifying innovative solutions to problems and putting forward plans for further experiments

  • Communicate experimental data and key findings in a clear and concise manner to project teams

  • Generate and maintain clear experimental records

  • Maintain an awareness of current developments in the literature to support projects, bring forward new target ideas or new technologies / assay methods

  • Actively drive personal development within Oncology Bioscience, independently identifying opportunities where relevant.

Essential for the role

  • Degree and PhD in cell biology, biochemistry, pharmacology or a related field with at least 6 years of lab based experience in the field of cancer research

  • Evidence of strong technical and experimental ability to deliver data from the lab

  • Expertise in mammalian cell line tissue culture techniques including cell line maintenance, transfection, transduction

  • Expertise in a range of in vitro cell based & mechanistic techniques and assays including cellular proliferation and survival assays, flow cytommetry and high-content imaging

  • Expertise in a range of molecular biological techniques including molecular cloning, isolation and analysis of nucleic acids and proteins

  • Strong communication and presentation skills

  • Positive and collaborative team player with willingness to improve and learn new skills

  • Passion for experimental work with a desire to pursue a career from the lab

  • Exellent understanding of cancer cell biology

Desirable for the role

  • Lab-based drug discovery experience in academic or pharmaceutical company setting

  • CRISPR gene editing and stable cell line generation

  • An understanding of the drug discovery process

  • Experience of analysing large data sets

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

  • Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

  • Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

  • If you’re curious to know more then please reach out to Louise Bennett

Competitive salary package and benefits

Close Date: 13/12/2021

“As part of the application process for some roles at AstraZeneca, candidates may be asked to complete a series of online games, created by pymetrics, to assess certain candidate qualities to help evaluate potential match for the position. If the pymetrics process applies to this role, you will receive an email invitation with additional information following application. Once completed AZ will automatically receive your results – pymetrics will not be used solely in our decision-making process but will help us gather additional insight.”

Where can I find out more?

Our Social Media,

Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

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