Senior Scientist, Assay (HCI), Biologics Engineering, Oncology

ABOUT ASTRAZENECA

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.

SITE DESCRIPTION

Welcome to Granta Park Cambridge, UK, one of over 400 sites here at AstraZeneca, providing a collaborative environment where everyone feels comfortable and able to be themselves is at the core of AstraZeneca’s priorities, it’s important to us that you bring your full self to work every day. To help you maintain your best self, here’s a sneak peek into some of the things this site provides for you… Granta Park has a newly built gym with swimming pool, nursery and central food hub accessible to staff as part of the science park facilities. We also have our own bistro and deli in the AstraZeneca buildings. There are regular ‘Lunch & Learn’ events and after work socials with snacks and drinks on the last Friday of every month. This is our biggest and most spacious lab site in Cambridge…come and join us!

BUSINESS AREA

Working as part of the Biologics Engineering team, you will be responsible for providing critical cell and biochemical assay expertise to deliver multiple biologics drug discovery and technology development projects using state of the art technologies. Working with disease-area experts, you will develop disease-relevant cell assays, screen antibody repertoires, and identify and validate molecular targets. This is a lab-based role involving independent design, execution and interpretation of scientific experiments, and effective communication of findings and recommendations as part of a multi-disciplinary project team. You will also contribute to the identification and development of ground breaking technologies that benefit biologics drug discovery and have a consistent track record of creatively solving scientific challenges.

What you’ll do

  • Develop high content image acquisition and analysis capabilities for use as biologics screens and pharmacological characterisation of biologics for drug discovery or technology development projects, delivering work on time and to budget

  • Develop biochemical and cell based 96 or 384 well binding and functional assays

  • Identify and develop new screening and automation technologies and processes

  • Maintain a well-developed understanding of approaches to biologics drug discovery and apply a broader functional knowledge to support the department

  • Identify creative solutions to assay, technology or drug discovery project problems

  • Provide input to peer reviewed publications, patents and participate at international conferences

  • Ensures own work, and work of peers, follows Good Laboratory Practice, Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations

Essential for the role

  • PhD or a BSc/MSc degree with significant proven experience.

  • Experience and technical knowledge of biologics assay development, screening and use of automation, with a dedication to quality and scientific rigor

  • Strong teammate with good communication skills and experience of working in multi-disciplinary teams.

  • Ability to tackle challenges creatively and contribute and improve assay technologies and processes

Desirable for the role

  • Hands on experience in high content image acquisition and analysis

  • Hands on experience in Cell line development

  • Recombinant protein generation and engineering experience

  • Primary and disease relevant functional cell assay development experience

  • New technology evaluation and implementation

  • Background in drug discovery and development in the pharmaceutical industry

  • Knowledge of biologics drug discovery and in vitro pharmacology

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

Close date: 03/03/2022

Competitive salary and benefits

So, what’s next?

  • Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

  • Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

  • If you’re curious to know more then please reach out to Louise Bennett.

Where can I find out more?

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